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1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) increases Carmofur stability and in vitro antiproliferative effect

Addition of DMPC considerably inhibits the degradation of Carmofur in neutral phosphate buffer solutions and this drug becomes less influenced by pH. Carmofur stabilization at neutral pH caused by DMPC addition for in vitro studies was characterized and monitored by (1)H NMR. Antiproliferative activ...

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Detalles Bibliográficos
Autores principales: Domracheva, Ilona, Muhamadejev, Ruslan, Petrova, Marina, Liepinsh, Edvards, Gulbe, Anita, Shestakova, Irina, Duburs, Gunars, Arsenyan, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598257/
https://www.ncbi.nlm.nih.gov/pubmed/28962371
http://dx.doi.org/10.1016/j.toxrep.2015.01.009