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Non-human primate and rodent embryonic stem cells are differentially sensitive to embryotoxic compounds

Many industrial chemicals and their respective by-products need to be comprehensively evaluated for toxicity using reliable and efficient assays. In terms of teratogenicity evaluations, the murine-based embryonic stem cell test (EST) offers a promising solution to screen for multiple tissue endpoint...

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Detalles Bibliográficos
Autores principales: Walker, Lauren, Baumgartner, Laura, Keller, Kevin C., Ast, Julia, Trettner, Susanne, zur Nieden, Nicole I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598278/
https://www.ncbi.nlm.nih.gov/pubmed/28962348
http://dx.doi.org/10.1016/j.toxrep.2014.11.016