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Toxicological evaluation of a novel cooling compound: 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide

A toxicological evaluation of a novel cooling agent, 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl) acetamide (S2227; CAS 1374760-95-8), was completed for the purpose of assessing its safety for use in food and beverage applications. S2227 undergoes rapid oxidative metabolism in vitro,...

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Detalles Bibliográficos
Autores principales: Karanewsky, Donald S., Arthur, Amy J., Liu, Hanghui, Chi, Bert, Markison, Stacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598389/
https://www.ncbi.nlm.nih.gov/pubmed/28962472
http://dx.doi.org/10.1016/j.toxrep.2015.09.001