Cargando…
Butafenacil: A positive control for identifying anemia- and variegate porphyria-inducing chemicals
Butafenacil is an herbicide that inhibits protoporphyrinogen oxidase (PPOX), an enzyme that catalyzes oxidation of protoporphyrinogen IX to protoporphyrin IX during chlorophyll and heme biosynthesis. Based on a high-content screen, we previously identified butafenacil as a potent inducer of anemia i...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598413/ https://www.ncbi.nlm.nih.gov/pubmed/28962437 http://dx.doi.org/10.1016/j.toxrep.2015.07.006 |