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Butafenacil: A positive control for identifying anemia- and variegate porphyria-inducing chemicals

Butafenacil is an herbicide that inhibits protoporphyrinogen oxidase (PPOX), an enzyme that catalyzes oxidation of protoporphyrinogen IX to protoporphyrin IX during chlorophyll and heme biosynthesis. Based on a high-content screen, we previously identified butafenacil as a potent inducer of anemia i...

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Detalles Bibliográficos
Autores principales:	Leet, Jessica K., Hipszer, Rachel A., Volz, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598413/ https://www.ncbi.nlm.nih.gov/pubmed/28962437 http://dx.doi.org/10.1016/j.toxrep.2015.07.006

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