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Chloroquine and hydroxychloroquine binding to melanin: Some possible consequences for pathologies
For many years chloroquine was used as a prophylactic agent against malaria, and more recently as a mild immunosuppressive. However, due to lengthy treatment periods, adverse effects have become apparent, which included retinopathy. The structurally related hydroxychloroquine is less toxic, thought...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598414/ https://www.ncbi.nlm.nih.gov/pubmed/28962308 http://dx.doi.org/10.1016/j.toxrep.2014.10.019 |