Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

Accumulating evidence reveals that DEP-domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in the pathogenesis and progression of many tumors. However, the expression level of DEPTOR and its function in the tumorigenesis of osteosarcoma (OS) remain unknown. In this study, we cond...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Binwu, Lv, Xiao, Gao, Feng, Chen, Songfeng, Wang, Shangyu, Qing, Xiangcheng, Liu, Jianxiang, Wang, Baichuan, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598754/
https://www.ncbi.nlm.nih.gov/pubmed/28932123
http://dx.doi.org/10.2147/OTT.S143518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598754/
https://www.ncbi.nlm.nih.gov/pubmed/28932123
http://dx.doi.org/10.2147/OTT.S143518

Ejemplares similares