Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis

BACKGROUND: Myeloid cells are central to atherosclerotic lesion development and vulnerable plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells (efferocytosis) promotes lesion growth and establishment of a necrotic core. The transcription factor interferon regulatory f...

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Detalles Bibliográficos
Autores principales: Seneviratne, Anusha N., Edsfeldt, Andreas, Cole, Jennifer E., Kassiteridi, Christina, Swart, Maarten, Park, Inhye, Green, Patricia, Khoyratty, Tariq, Saliba, David, Goddard, Michael E., Sansom, Stephen N., Goncalves, Isabel, Krams, Rob, Udalova, Irina A., Monaco, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598917/
https://www.ncbi.nlm.nih.gov/pubmed/28698173
http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598917/
https://www.ncbi.nlm.nih.gov/pubmed/28698173
http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027844

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