Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

Bile salt hydrolase (BSH) activity against the bile acid tauro-beta-muricholic acid (T-β-MCA) was recently reported to mediate host bile acid, glucose, and lipid homeostasis via the farnesoid X receptor (FXR) signaling pathway. An earlier study correlated decreased Lactobacillus abundance in the cec...

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Detalles Bibliográficos
Autores principales: DiMarzio, Michael, Rusconi, Brigida, Yennawar, Neela H., Eppinger, Mark, Patterson, Andrew D., Dudley, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598929/
https://www.ncbi.nlm.nih.gov/pubmed/28910295
http://dx.doi.org/10.1371/journal.pone.0183564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598929/
https://www.ncbi.nlm.nih.gov/pubmed/28910295
http://dx.doi.org/10.1371/journal.pone.0183564

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