Gugulipid causes hypercholesterolemia leading to endothelial dysfunction, increased atherosclerosis, and premature death by ischemic heart disease in male mice

For proper cholesterol metabolism, normal expression and function of scavenger receptor class B type I (SR-BI), a high-density lipoprotein (HDL) receptor, is required. Among the factors that regulate overall cholesterol homeostasis and HDL metabolism, the nuclear farnesoid X receptor plays an import...

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Detalles Bibliográficos
Autores principales: Leiva, Andrea, Contreras-Duarte, Susana, Amigo, Ludwig, Sepúlveda, Esteban, Boric, Mauricio, Quiñones, Verónica, Busso, Dolores, Rigotti, Attilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598962/
https://www.ncbi.nlm.nih.gov/pubmed/28910310
http://dx.doi.org/10.1371/journal.pone.0184280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598962/
https://www.ncbi.nlm.nih.gov/pubmed/28910310
http://dx.doi.org/10.1371/journal.pone.0184280

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