Src- and Fyn-dependent apical membrane trafficking events control endothelial lumen formation during vascular tube morphogenesis

Here we examine the question of how endothelial cells (ECs) develop their apical membrane surface domain during lumen and tube formation. We demonstrate marked apical membrane targeting of activated Src kinases to this apical domain during early and late stages of this process. Immunostaining for ph...

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Detalles Bibliográficos
Autores principales: Kim, Dae Joong, Norden, Pieter R., Salvador, Jocelynda, Barry, David M., Bowers, Stephanie L. K., Cleaver, Ondine, Davis, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598984/
https://www.ncbi.nlm.nih.gov/pubmed/28910325
http://dx.doi.org/10.1371/journal.pone.0184461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598984/
https://www.ncbi.nlm.nih.gov/pubmed/28910325
http://dx.doi.org/10.1371/journal.pone.0184461

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