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Src- and Fyn-dependent apical membrane trafficking events control endothelial lumen formation during vascular tube morphogenesis
Here we examine the question of how endothelial cells (ECs) develop their apical membrane surface domain during lumen and tube formation. We demonstrate marked apical membrane targeting of activated Src kinases to this apical domain during early and late stages of this process. Immunostaining for ph...
Autores principales: | Kim, Dae Joong, Norden, Pieter R., Salvador, Jocelynda, Barry, David M., Bowers, Stephanie L. K., Cleaver, Ondine, Davis, George E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598984/ https://www.ncbi.nlm.nih.gov/pubmed/28910325 http://dx.doi.org/10.1371/journal.pone.0184461 |
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