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PI3K-C2α knockdown decreases autophagy and maturation of endocytic vesicles

Phosphoinositide 3-kinase (PI3K) family members are involved in diverse cellular fates including cell growth, proliferation, and survival. While many molecular details are known about the Class I and III PI3Ks, less is known about the Class II PI3Ks. To explore the function of all eight PI3K isoform...

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Detalles Bibliográficos
Autores principales: Merrill, Nathan M., Schipper, Joshua L., Karnes, Jonathan B., Kauffman, Audra L., Martin, Katie R., MacKeigan, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599018/
https://www.ncbi.nlm.nih.gov/pubmed/28910396
http://dx.doi.org/10.1371/journal.pone.0184909