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The effect of S-substitution at the O6-guanine site on the structure and dynamics of a DNA oligomer containing a G:T mismatch

The effect of S-substitution on the O(6) guanine site of a 13-mer DNA duplex containing a G:T mismatch is studied using molecular dynamics. The structure, dynamic evolution and hydration of the S-substituted duplex are compared with those of a normal duplex, a duplex with S-substitution on guanine,...

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Detalles Bibliográficos
Autores principales: Moore, Elaine Ann, Xu, Yao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599020/
https://www.ncbi.nlm.nih.gov/pubmed/28910418
http://dx.doi.org/10.1371/journal.pone.0184801