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Genotypic characterization directly applied to sputum improves the detection of Mycobacterium africanum West African 1, under-represented in positive cultures

BACKGROUND: This study aimed to compare the prevalence of Mycobacterium tuberculosis complex (MTBc) lineages between direct genotyping (on sputum) and indirect genotyping (on culture), to characterize potential culture bias against difficult growers. METHODOLOGY/PRINCIPAL FINDINGS: Smear-positive sp...

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Detalles Bibliográficos
Autores principales: Sanoussi, C. N’Dira, Affolabi, Dissou, Rigouts, Leen, Anagonou, Séverin, de Jong, Bouke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599059/
https://www.ncbi.nlm.nih.gov/pubmed/28863143
http://dx.doi.org/10.1371/journal.pntd.0005900