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A single Markov-type kinetic model accounting for the macroscopic currents of all human voltage-gated sodium channel isoforms
Modelling ionic channels represents a fundamental step towards developing biologically detailed neuron models. Until recently, the voltage-gated ion channels have been mainly modelled according to the formalism introduced by the seminal works of Hodgkin and Huxley (HH). However, following the contin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599066/ https://www.ncbi.nlm.nih.gov/pubmed/28863150 http://dx.doi.org/10.1371/journal.pcbi.1005737 |