A single Markov-type kinetic model accounting for the macroscopic currents of all human voltage-gated sodium channel isoforms

Modelling ionic channels represents a fundamental step towards developing biologically detailed neuron models. Until recently, the voltage-gated ion channels have been mainly modelled according to the formalism introduced by the seminal works of Hodgkin and Huxley (HH). However, following the contin...

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Detalles Bibliográficos
Autores principales: Balbi, Pietro, Massobrio, Paolo, Hellgren Kotaleski, Jeanette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599066/
https://www.ncbi.nlm.nih.gov/pubmed/28863150
http://dx.doi.org/10.1371/journal.pcbi.1005737

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