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Epstein Barr virus Latent Membrane Protein-1 enhances dendritic cell therapy lymph node migration, activation, and IL-12 secretion

Dendritic cells (DC) are a promising cell type for cancer vaccines due to their high immunostimulatory capacity. However, improper maturation of DC prior to treatment may account for the limited efficacy of DC vaccine clinical trials. Latent Membrane Protein-1 (LMP1) of Epstein-Barr virus was examin...

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Detalles Bibliográficos
Autores principales: Termini, James M., Gupta, Sachin, Raffa, Francesca N., Guirado, Elizabeth, Fischl, Margaret A., Niu, Liguo, Kanagavelu, Saravana, Stone, Geoffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599068/
https://www.ncbi.nlm.nih.gov/pubmed/28910387
http://dx.doi.org/10.1371/journal.pone.0184915