Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L

Organogenesis and tissue development occur through sequential stepwise processes leading to increased lineage restriction and loss of pluripotency. An exception to this appears in the adult human breast, where rare variant epithelial cells exhibit pluripotency and multilineage differentiation potent...

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Detalles Bibliográficos
Autores principales: Breindel, Jerrica L., Skibinski, Adam, Sedic, Maja, Wronski-Campos, Ania, Zhou, Wenhui, Keller, Patricia J., Mills, Joslyn, Bradner, James, Onder, Tamer, Kuperwasser, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599181/
https://www.ncbi.nlm.nih.gov/pubmed/28781076
http://dx.doi.org/10.1016/j.stemcr.2017.06.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599181/
https://www.ncbi.nlm.nih.gov/pubmed/28781076
http://dx.doi.org/10.1016/j.stemcr.2017.06.019

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