Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis

Hematopoietic stem cells arise from mesoderm-derived hemogenic endothelium (HE) during embryogenesis in a process termed endothelial-hematopoietic transition (EHT). To better understand the gene networks that control this process, we investigated the role of the transcription factor HEB (TCF12) by d...

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Detalles Bibliográficos
Autores principales: Li, Yang, Brauer, Patrick M., Singh, Jastaranpreet, Xhiku, Sintia, Yoganathan, Kogulan, Zúñiga-Pflücker, Juan Carlos, Anderson, Michele K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599183/
https://www.ncbi.nlm.nih.gov/pubmed/28803914
http://dx.doi.org/10.1016/j.stemcr.2017.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599183/
https://www.ncbi.nlm.nih.gov/pubmed/28803914
http://dx.doi.org/10.1016/j.stemcr.2017.07.011

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