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Activin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation

In vitro differentiation of mouse embryonic stem cells (ESCs) into retinal fates can be used to study the roles of exogenous factors acting through multiple signaling pathways during retina development. Application of activin A during a specific time frame that corresponds to early embryonic retinog...

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Detalles Bibliográficos
Autores principales: Lu, Amy Q., Popova, Evgenya Y., Barnstable, Colin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599185/
https://www.ncbi.nlm.nih.gov/pubmed/28781074
http://dx.doi.org/10.1016/j.stemcr.2017.06.021