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Cancer stem cells: understanding tumor hierarchy and heterogeneity
Heterogeneity within and between tumors is a well-known phenomenon that greatly complicates the diagnosis and treatment of cancer. A large body of research indicates that heterogeneity develops through time as tumor-initiating stem cells, also known as cancer stem cells (CSCs), evolve genetic or epi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer Health
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599210/ https://www.ncbi.nlm.nih.gov/pubmed/27611934 http://dx.doi.org/10.1097/MD.0000000000004764 |