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Cancer stem cells: understanding tumor hierarchy and heterogeneity

Heterogeneity within and between tumors is a well-known phenomenon that greatly complicates the diagnosis and treatment of cancer. A large body of research indicates that heterogeneity develops through time as tumor-initiating stem cells, also known as cancer stem cells (CSCs), evolve genetic or epi...

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Detalles Bibliográficos
Autor principal: Rich, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599210/
https://www.ncbi.nlm.nih.gov/pubmed/27611934
http://dx.doi.org/10.1097/MD.0000000000004764