JMJD1C Ensures Mouse Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming through Controlling MicroRNA Expression

The roles of histone demethylases (HDMs) for the establishment and maintenance of pluripotency are incompletely characterized. Here, we show that JmjC-domain-containing protein 1c (JMJD1C), an H3K9 demethylase, is required for mouse embryonic stem cell (ESC) self-renewal. Depletion of Jmjd1c leads t...

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Detalles Bibliográficos
Autores principales: Xiao, Feng, Liao, Bing, Hu, Jing, Li, Shuang, Zhao, Haixin, Sun, Ming, Gu, Junjie, Jin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599225/
https://www.ncbi.nlm.nih.gov/pubmed/28826851
http://dx.doi.org/10.1016/j.stemcr.2017.07.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599225/
https://www.ncbi.nlm.nih.gov/pubmed/28826851
http://dx.doi.org/10.1016/j.stemcr.2017.07.013

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