Control of AMPA receptor activity by the extracellular loops of auxiliary proteins

At synapses throughout the mammalian brain, AMPA receptors form complexes with auxiliary proteins, including TARPs. However, how TARPs modulate AMPA receptor gating remains poorly understood. We built structural models of TARP-AMPA receptor complexes for TARPs γ2 and γ8, combining recent structural...

Descripción completa

Detalles Bibliográficos
Autores principales: Riva, Irene, Eibl, Clarissa, Volkmer, Rudolf, Carbone, Anna L, Plested, Andrew JR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599240/
https://www.ncbi.nlm.nih.gov/pubmed/28871958
http://dx.doi.org/10.7554/eLife.28680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599240/
https://www.ncbi.nlm.nih.gov/pubmed/28871958
http://dx.doi.org/10.7554/eLife.28680

Ejemplares similares