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Control of AMPA receptor activity by the extracellular loops of auxiliary proteins
At synapses throughout the mammalian brain, AMPA receptors form complexes with auxiliary proteins, including TARPs. However, how TARPs modulate AMPA receptor gating remains poorly understood. We built structural models of TARP-AMPA receptor complexes for TARPs γ2 and γ8, combining recent structural...
Autores principales: | Riva, Irene, Eibl, Clarissa, Volkmer, Rudolf, Carbone, Anna L, Plested, Andrew JR |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599240/ https://www.ncbi.nlm.nih.gov/pubmed/28871958 http://dx.doi.org/10.7554/eLife.28680 |
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