Cytoplasmic and Nuclear TAZ Exert Distinct Functions in Regulating Primed Pluripotency

Mouse epiblast stem cells (mEpiSCs) and human embryonic stem cells (hESCs) are primed pluripotent stem cells whose self-renewal can be maintained through cytoplasmic stabilization and retention of β-catenin. The underlying mechanism, however, remains largely unknown. Here, we show that cytoplasmic β...

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Detalles Bibliográficos
Autores principales: Zhou, Xingliang, Chadarevian, Jean Paul, Ruiz, Bryan, Ying, Qi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599246/
https://www.ncbi.nlm.nih.gov/pubmed/28844657
http://dx.doi.org/10.1016/j.stemcr.2017.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599246/
https://www.ncbi.nlm.nih.gov/pubmed/28844657
http://dx.doi.org/10.1016/j.stemcr.2017.07.019

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