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Cytoplasmic and Nuclear TAZ Exert Distinct Functions in Regulating Primed Pluripotency
Mouse epiblast stem cells (mEpiSCs) and human embryonic stem cells (hESCs) are primed pluripotent stem cells whose self-renewal can be maintained through cytoplasmic stabilization and retention of β-catenin. The underlying mechanism, however, remains largely unknown. Here, we show that cytoplasmic β...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599246/ https://www.ncbi.nlm.nih.gov/pubmed/28844657 http://dx.doi.org/10.1016/j.stemcr.2017.07.019 |