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Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons

Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases. To date, it has been possible to obtain GABAergic and glutamatergic neurons via...

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Detalles Bibliográficos
Autores principales: Pereira, Maria, Birtele, Marcella, Shrigley, Shelby, Benitez, Julio Aguila, Hedlund, Eva, Parmar, Malin, Ottosson, Daniella Rylander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599255/
https://www.ncbi.nlm.nih.gov/pubmed/28844658
http://dx.doi.org/10.1016/j.stemcr.2017.07.023