Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α

The generation of functional arterial endothelial cells (aECs) from embryonic stem cells (ESCs) holds great promise for vascular tissue engineering. However, the mechanisms underlying their generation and the potential of aECs in revascularizing ischemic tissue are not fully understood. Here, we obs...

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Detalles Bibliográficos
Autores principales: Tsang, Kit Man, Hyun, James S., Cheng, Kwong Tai, Vargas, Micaela, Mehta, Dolly, Ushio-Fukai, Masuko, Zou, Li, Pajcini, Kostandin V., Rehman, Jalees, Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599266/
https://www.ncbi.nlm.nih.gov/pubmed/28781077
http://dx.doi.org/10.1016/j.stemcr.2017.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599266/
https://www.ncbi.nlm.nih.gov/pubmed/28781077
http://dx.doi.org/10.1016/j.stemcr.2017.07.001

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