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A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

Development of safe and effective stem cell-based therapies for brain repair requires an in-depth understanding of the in vivo properties of neural grafts generated from human stem cells. Replacing dopamine neurons in Parkinson's disease remains one of the most anticipated applications. Here, w...

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Detalles Bibliográficos
Autores principales: Niclis, Jonathan C., Gantner, Carlos W., Hunt, Cameron P.J., Kauhausen, Jessica A., Durnall, Jennifer C., Haynes, John M., Pouton, Colin W., Parish, Clare L., Thompson, Lachlan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599268/
https://www.ncbi.nlm.nih.gov/pubmed/28867345
http://dx.doi.org/10.1016/j.stemcr.2017.08.002