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The schizophrenia and autism associated gene, Transcription Factor 4 (TCF4) regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner
Disruption of the laminar and columnar organization of the brain is implicated in several psychiatric disorders. Here, we show in utero gain-of-function of the psychiatric risk gene transcription factor 4 (TCF4) severely disrupts the columnar organization of medial prefrontal cortex (mPFC) in a tran...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599320/ https://www.ncbi.nlm.nih.gov/pubmed/28289282 http://dx.doi.org/10.1038/mp.2017.37 |