The schizophrenia and autism associated gene, Transcription Factor 4 (TCF4) regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner

Disruption of the laminar and columnar organization of the brain is implicated in several psychiatric disorders. Here, we show in utero gain-of-function of the psychiatric risk gene transcription factor 4 (TCF4) severely disrupts the columnar organization of medial prefrontal cortex (mPFC) in a tran...

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Detalles Bibliográficos
Autores principales: Page, Stephanie Cerceo, Hamersky, Gregory R., Gallo, Ryan A., Rannals, Matthew D., Calcaterra, Nicolas E., Campbell, Morganne N., Mayfield, Brent, Briley, Aaron, Phan, BaDoi N., Jaffe, Andrew E., Maher, Brady J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599320/
https://www.ncbi.nlm.nih.gov/pubmed/28289282
http://dx.doi.org/10.1038/mp.2017.37

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