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Histone Deacetylase Adaptation in Single Ventricle Heart Disease and a Young Animal Model of Right Ventricular Hypertrophy

BACKGROUND: Histone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac disease. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle heart disease of right ventricular morphology (SV), as well as i...

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Detalles Bibliográficos
Autores principales: Blakeslee, Weston W., Demos-Davies, Kimberly M., Lemon, Douglas D., Lutter, Katharina M., Cavasin, Maria A., Payne, Sam, Nunley, Karin, Long, Carlin S., McKinsey, Timothy A., Miyamoto, Shelley D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599335/
https://www.ncbi.nlm.nih.gov/pubmed/28549058
http://dx.doi.org/10.1038/pr.2017.126