PK/PD studies on non-selective PDE inhibitors in rats using cAMP as a marker of pharmacological response

In recent years, phosphodiesterase (PDE) inhibitors have been frequently tested for the treatment of experimental inflammatory and immune disorders. It is suggested that anti-inflammatory properties of PDE inhibitors are related to their ability to increase cAMP levels. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Świerczek, Artur, Wyska, Elżbieta, Baś, Sebastian, Woyciechowska, Marta, Mlynarski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599463/
https://www.ncbi.nlm.nih.gov/pubmed/28730281
http://dx.doi.org/10.1007/s00210-017-1406-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599463/
https://www.ncbi.nlm.nih.gov/pubmed/28730281
http://dx.doi.org/10.1007/s00210-017-1406-z

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