Calcium/calmodulin‐dependent kinase 2 mediates Epac‐induced spontaneous transient outward currents in rat vascular smooth muscle

KEY POINTS: The Ca(2+) and redox‐sensing enzyme Ca(2+)/calmodulin‐dependent kinase 2 (CaMKII) is a crucial and well‐established signalling molecule in the heart and brain. In vascular smooth muscle, which controls blood flow by contracting and relaxing in response to complex Ca(2+) signals and oxida...

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Detalles Bibliográficos
Autores principales: Humphries, Edward S. A., Kamishima, Tomoko, Quayle, John M., Dart, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599484/
https://www.ncbi.nlm.nih.gov/pubmed/28731505
http://dx.doi.org/10.1113/JP274754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599484/
https://www.ncbi.nlm.nih.gov/pubmed/28731505
http://dx.doi.org/10.1113/JP274754

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