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Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization

Our previous study demonstrated that the sigma-1 receptor is involved in methamphetamine-induced microglial apoptosis and death; however, whether the sigma-1 receptor is involved in microglial activation as well as the molecular mechanisms underlying this process remains poorly understood. The aim o...

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Detalles Bibliográficos
Autores principales: Chao, Jie, Zhang, Yuan, Du, Longfei, Zhou, Rongbin, Wu, Xiaodong, Shen, Kai, Yao, Honghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599501/
https://www.ncbi.nlm.nih.gov/pubmed/28912535
http://dx.doi.org/10.1038/s41598-017-11065-8