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Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test

The spatial organization of the genome plays a critical role in regulating gene expression. Recent chromatin interaction mapping studies have revealed that topologically associating domains and subdomains are fundamental building blocks of the three-dimensional genome. Identifying such hierarchical...

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Detalles Bibliográficos
Autores principales: Yu, Wenbao, He, Bing, Tan, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599511/
https://www.ncbi.nlm.nih.gov/pubmed/28912419
http://dx.doi.org/10.1038/s41467-017-00478-8