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Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test
The spatial organization of the genome plays a critical role in regulating gene expression. Recent chromatin interaction mapping studies have revealed that topologically associating domains and subdomains are fundamental building blocks of the three-dimensional genome. Identifying such hierarchical...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599511/ https://www.ncbi.nlm.nih.gov/pubmed/28912419 http://dx.doi.org/10.1038/s41467-017-00478-8 |