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Peripheral human CD4(+)CD8(+) T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15

CD4(+)CD8(+) T lymphocytes account for 1–2% of circulating human T lymphocytes, but their frequency is augmented in several diseases. The phenotypic and functional properties of these T lymphocytes are still ill-defined. We performed an ex vivo characterization of CD4(+)CD8(+) T lymphocytes from the...

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Detalles Bibliográficos
Autores principales: Clénet, Marie-Laure, Gagnon, François, Moratalla, Ana Carmena, Viel, Emilie C., Arbour, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599513/
https://www.ncbi.nlm.nih.gov/pubmed/28912605
http://dx.doi.org/10.1038/s41598-017-11926-2