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A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment

The ETS transcription factor Etv2 is necessary and sufficient for the generation of hematopoietic and endothelial cells. However, upstream regulators of Etv2 in hemangiogenesis, generation of hematopoietic and endothelial cells, have not been clearly addressed. Here we track the developmental route...

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Detalles Bibliográficos
Autores principales: Zhao, Haiyong, Choi, Kyunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599515/
https://www.ncbi.nlm.nih.gov/pubmed/28912455
http://dx.doi.org/10.1038/s41467-017-00667-5