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A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment
The ETS transcription factor Etv2 is necessary and sufficient for the generation of hematopoietic and endothelial cells. However, upstream regulators of Etv2 in hemangiogenesis, generation of hematopoietic and endothelial cells, have not been clearly addressed. Here we track the developmental route...
Autores principales: | Zhao, Haiyong, Choi, Kyunghee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599515/ https://www.ncbi.nlm.nih.gov/pubmed/28912455 http://dx.doi.org/10.1038/s41467-017-00667-5 |
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