CScape: a tool for predicting oncogenic single-point mutations in the cancer genome

For somatic point mutations in coding and non-coding regions of the genome, we propose CScape, an integrative classifier for predicting the likelihood that mutations are cancer drivers. Tested on somatic mutations, CScape tends to outperform alternative methods, reaching 91% balanced accuracy in cod...

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Detalles Bibliográficos
Autores principales: Rogers, Mark F., Shihab, Hashem A., Gaunt, Tom R., Campbell, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599557/
https://www.ncbi.nlm.nih.gov/pubmed/28912487
http://dx.doi.org/10.1038/s41598-017-11746-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599557/
https://www.ncbi.nlm.nih.gov/pubmed/28912487
http://dx.doi.org/10.1038/s41598-017-11746-4

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