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Kinetic adaptation of human Myo19 for active mitochondrial transport to growing filopodia tips

Myosins are actin-based molecular motors which are enzymatically adapted for their cellular functions such as transportation and membrane tethering. Human Myo19 affects mitochondrial motility, and promotes their localization to stress-induced filopodia. Therefore, studying Myo19 enzymology is essent...

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Detalles Bibliográficos
Autores principales: Ušaj, Marko, Henn, Arnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599584/
https://www.ncbi.nlm.nih.gov/pubmed/28912602
http://dx.doi.org/10.1038/s41598-017-11984-6