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DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma

Epigenetic deregulation is a hallmark of cancer characterized by frequent acquisition of new DNA methylation in CpG islands. To gain insight into the methylation changes of canine DLBCL, we investigated the DNA methylome in primary DLBCLs in comparison with control lymph nodes by genome-wide CpG mic...

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Detalles Bibliográficos
Autores principales: Ferraresso, Serena, Aricò, Arianna, Sanavia, Tiziana, Da Ros, Silvia, Milan, Massimo, Cascione, Luciano, Comazzi, Stefano, Martini, Valeria, Giantin, Mery, Di Camillo, Barbara, Mazzariol, Sandro, Giannuzzi, Diana, Marconato, Laura, Aresu, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599585/
https://www.ncbi.nlm.nih.gov/pubmed/28912427
http://dx.doi.org/10.1038/s41598-017-11724-w