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Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

Extracellular vesicles (EVs) play a pivotal role in cell-to-cell communication and have been shown to take part in several physiological and pathological processes. EVs have traditionally been purified by ultracentrifugation (UC), however UC has limitations, including resulting in, operator-dependan...

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Detalles Bibliográficos
Autores principales: Corso, Giulia, Mäger, Imre, Lee, Yi, Görgens, André, Bultema, Jarred, Giebel, Bernd, Wood, Matthew J. A., Nordin, Joel Z., Andaloussi, Samir EL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599601/
https://www.ncbi.nlm.nih.gov/pubmed/28912498
http://dx.doi.org/10.1038/s41598-017-10646-x