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Cleavage of 3′-terminal adenosine by archaeal ATP-dependent RNA ligase

Methanothermobacter thermoautotrophicus RNA ligase (MthRnl) catalyzes formation of phosphodiester bonds between the 5′-phosphate and 3′-hydroxyl termini of single-stranded RNAs. It can also react with RNA with a 3′-phosphate end to generate a 2′,3′-cyclic phosphate. Here, we show that MthRnl can add...

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Detalles Bibliográficos
Autores principales: Yoshinari, Shigeo, Liu, Yancheng, Gollnick, Paul, Ho, C. Kiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599603/
https://www.ncbi.nlm.nih.gov/pubmed/28912583
http://dx.doi.org/10.1038/s41598-017-11693-0