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The Homologous Recombination Machinery Orchestrates Post-replication DNA Repair During Self-renewal of Mouse Embryonic Stem Cells

Embryonic stem (ES) cells require homologous recombination (HR) to cope with genomic instability caused during self-renewal. Here, we report expression dynamics and localization of endogenous HR factors in DNA break repair of ES cells. In addition, we analyzed gene expression patterns of HR-related...

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Detalles Bibliográficos
Autores principales: Choi, Eui-Hwan, Yoon, Seobin, Park, Kyung-Soon, Kim, Keun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599617/
https://www.ncbi.nlm.nih.gov/pubmed/28912486
http://dx.doi.org/10.1038/s41598-017-11951-1