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The Homologous Recombination Machinery Orchestrates Post-replication DNA Repair During Self-renewal of Mouse Embryonic Stem Cells
Embryonic stem (ES) cells require homologous recombination (HR) to cope with genomic instability caused during self-renewal. Here, we report expression dynamics and localization of endogenous HR factors in DNA break repair of ES cells. In addition, we analyzed gene expression patterns of HR-related...
Autores principales: | Choi, Eui-Hwan, Yoon, Seobin, Park, Kyung-Soon, Kim, Keun P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599617/ https://www.ncbi.nlm.nih.gov/pubmed/28912486 http://dx.doi.org/10.1038/s41598-017-11951-1 |
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