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Matrisome Profiling During Intervertebral Disc Development And Ageing

Intervertebral disc (IVD) degeneration is often the cause of low back pain. Degeneration occurs with age and is accompanied by extracellular matrix (ECM) depletion, culminating in nucleus pulpous (NP) extrusion and IVD destruction. The changes that occur in the disc with age have been under investig...

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Detalles Bibliográficos
Autores principales: Caldeira, Joana, Santa, Cátia, Osório, Hugo, Molinos, Maria, Manadas, Bruno, Gonçalves, Raquel, Barbosa, Mário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599645/
https://www.ncbi.nlm.nih.gov/pubmed/28912585
http://dx.doi.org/10.1038/s41598-017-11960-0