Endogenous ω-3 Fatty Acid Production by fat-1 Transgene and Topically Applied Docosahexaenoic Acid Protect against UVB-induced Mouse Skin Carcinogenesis

The present study was intended to explore the effects of endogenously produced ω-3 polyunsaturated fatty acids (PUFAs) on ultraviolet B (UVB)-induced skin inflammation and photocarcinogenesis using hairless fat-1 transgenic mice harboring ω-3 desaturase gene capable of converting ω-6 to ω-3 PUFAs. U...

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Detalles Bibliográficos
Autores principales: Yum, Hye-Won, Park, Jin, Park, Hyun-Jung, Shin, Jun Wan, Cho, Yong-Yeon, Kim, Su-Jung, Kang, Jing X., Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599646/
https://www.ncbi.nlm.nih.gov/pubmed/28912452
http://dx.doi.org/10.1038/s41598-017-11443-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599646/
https://www.ncbi.nlm.nih.gov/pubmed/28912452
http://dx.doi.org/10.1038/s41598-017-11443-2

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